The Scientist : NewsBlog Print: MS drug sickens patient...again
The Scientist: NewsBlog:
MS drug sickens patient...again
[Entry posted at 16th December 2008 04:27 PM GMT]

Another case of a potentially fatal brain infection has been reported in a patient taking the multiple sclerosis drug Tysabri, the biotech who developed the drug announced yesterday.

This is the fourth case of infection, called progressive multifocal leukoencephalopathy (PML) this year. They are the only cases reported since the drug was taken off the market in 2005 because of three cases of infection. The FDA allowed Tysabri back on the market in 2006 with restrictions and stronger warnings. Regulators have still not been able to understand the link between the drug -- a monoclonal antibody -- and the brain infections.

A spokeswoman for the drug's manufacturer, Biogen Idec Inc, Naomi Aoki, said the drug's effectiveness at preventing relapses of multiple sclerosis symptoms justifies its use, despite the relatively low risk of PML, according to Reuters. About 35,000 patients worldwide are taking Tysabri.

PML is a viral disease that infects and damages the white matter of the brain, usually affecting people who are immunosuppressed.


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    [26 February 2008]


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    Drug addict on sucidal maniac observed by droping head line of palm print
    by Sankara Velayudhan Nandakumar

    [Comment posted 2008-12-18 23:08:08]
    This information is very important and the attention it desreves on Neuron behaviour as observed by inverted cubical curve formed as indicated in the brain line drooping towards lunar mount.The brain line or head line deviate between upper push or downward push due to lunar attraction on neuron square towards cross oscillation corresponding to suicidal maniac ,a mental depression out of control during full moon and new moon days which requires SQUID magnetic field emission of neurons which can be minimised by intensive yoga practice by stimulating the third eye which is also possble by laser biostimulation with crystals such as amethyst,azurite pyramid lattice which you can wear over your head,out of crystal generators or by magnetic field eraser system dynamics.
    S.Nandakumar on behalf of Oxford astrogenetics dept,uk.


    This drug works the best.
    by anonymous poster

    [Comment posted 2008-12-17 13:41:39]
    With the drug management program now in effect for MS users of Tysarbri, no one has died from PML. The drug has been identified as the most effective treatment for MS. Users who were in wheelchairs are walking.
    Check out Elan's website, www.elan.com, for more information.
    There's a lot of information out there which addresses the positive aspects of this miracle drug. The FDA has accepted the 1 in a 1000 chance of PML on the label, but with 35,000 patients on the drug the PML issue hasn't even come close to one in a thousand.


    Newly diagnosed MS
    by anonymous poster

    [Comment posted 2008-12-16 17:23:38]
    I am dismayed that there have not been any significant studies on the role of food, food allergies and immune responses that cross the blood brain barrier in treating MS. Just because it's difficult to make a buck off of food research, does not mean the research could not be invaluable to MS patients like me. Anyone interested in actually finding a causation rather than just treating the symptoms?


    Brain without leukocytes
    by Ellen Hunt

    [Comment posted 2008-12-16 15:12:43]
    Natalizumab acts against alpha-integrin. That results in interference with migration of leukocytes into organs. So a mild infection cannot be responded to and becomes destructive.


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