Over a career that spans more than half a century, John Holland,
a professor of psychology, electrical engineering, and computer science, invented
genetic algorithms, or computer code inspired by evolutionary biology. A MacArthur
fellowship recipient, Holland is "really not quite sure" how he became interested in
biology, but says he remembers being hooked by "the notion of combining mathematics
and biology" while reading R. A. Fisher's Genetical Theory of Natural
Selection. On page 36, Holland describes the application of genetic
algorithms to the field of complex adaptive systems, such as the immune system. Next
February, Holland will celebrate his 80th birthday in styleᅠ-ᅠat a conference in his
honor hosted by Nanyang Technological University in Singapore.
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Alexander Grimwade, a 30-year veteran of science and medical
publishing, has worked for various companies across Europe and the United States,
including Elsevier and Nature, and was publisher at The Scientist from
1998 to 2004. Grimwade now owns and operates a consulting business, AMG Science
Publishing, and runs The Scientist's annual Best Places to Work
surveys. In this month's issue, Grimwade administered and analyzed results from the
Salary Survey (p. 45), which polled life scientists across fields, with different
levels of experience, about their income. "I was pleased about the cooperation of
five of the major scientific societies in helping us to promote the survey to
members," he says.
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Robert Pacifici built a career in the thick of drug development
at pharmaceutical giants Eli Lilly and Amgen, as well as a private biotech company,
Xencor. In 2004, Pacifici became Chief Scientific Officer at CHDI, Inc., a
foundation devoted to drug discovery and development for Huntington's disease. On
page 28, Pacifici and co-author David Rankin discuss the benefits and challenges of
virtual biotechs as enterprises to fast-track development of therapies for rare
diseases. "The only thing that stands between us and success is the science," says
Pacifici.
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Portland illustrator Jordan Domont traces his artistic origins
to drawing comic book characters as a kid. Encouraged by his stepbrother to pursue
art, Domont completed a BFA in painting at the University of Oregon, and today the
27-year-old illustrates for magazines such as Business Week and
Atlanta Magazine. Domont's medium of choice is colored ink on
mylar, a plastic sheet material that doesn't absorb ink, so it can be layered, but
not always controlled. "It's really unpredictable," he says. "I never really know
what these paintings are going to look like until they're finished." Domont created
the image that graces this month's cover, as well as portraits of four people who
shape science policy from behind the scenes (p. 30).