The Citric Acid Cycle

The reductive citric acid cycle behaves like a chemical hurricane. Carbon atoms from CO 2 (yellow and orange) attach at either end of molecules. As the cycle proceeds (counterclockwise), they are drawn toward the interior (red) until the molecule splits at the top of the cycle, creating two smaller molecules (curved arrow), which then repeat the cycle.

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Chemical Hurricane
by Terry McGeary

[Comment posted 2008-07-02 10:51:34]
I have been teaching this part of biochemistry in college for decades and find this so-called 'hurricane' model neither enlightening nor useful in any way. I try to push the importance of H and the cytochrome system in ATP production through oxidative phosphorylation. This roundabout(carousel) seems to attempt to mystify or confuse.



Intelligent design
by Larry Barnes

[Comment posted 2008-06-18 16:11:21]
And who designed the designer?



Enzymes?
by NADIR MRABET

[Comment posted 2008-06-17 13:42:34]
I must post the earlier reference below:
David S. Ross in Origins of Life and Evolution of Biospheres, Volume 37, Number 1 / f←vrier 2007, pp. 61-65. The author states in the abstract "It is thus highly doubtful that the [reductive citric acid] cycle can operate at suitable rates without enzymes, and most unlikely that it could have participated in the chemistry leading to life."

Therefore, to my opinion, the interesting article by Eric Smith, raises the question about what arose first: (proto-)enzymes or substrates/products of the citric acid cycle? Even before the very first proto-cell!



Evolution
by Don Martini

[Comment posted 2008-06-09 17:15:32]
Whenever I see something on evolution I understand its an industry and if some lies are invalid research are not pushed on the public the researchers can't get grant money. However, I believe it's the worst pagan doctrine to take Jehovah's God's name from his creation. Furthermore, anyone debating the issue would lose because it has no facts. One of England's most eminent astromers, Sir Bernard Lovell, wrote of his "rapturous amazement at the harmony of natural law, which reveals an intelligence of such superiority that, compared with it, all the systematic thinking and acting of human beings is an utterly insignificant reflection."

Just consider that in a living cell 1/1,000 inch in diamaeter are as many as 200 trillion molecules around a nucleus 1/4000 inch in diameter. Within are the nucleuic acids, RNA/DNA which contain data sufficient to fill, if written out, a thousand 600 page books. Chemical reactions transact at the rate of thousands per second; manufacturing, communication, reproduction, digestion, excretion, and these involve hundreds of enzymes which the cell itself produces constantly.

You, you the collection of 100 trillion such cell-universes, are invested with miraculous conscious intelligence. To deny this evidence of astonishing design and inguinity is a problem of psychologic prejuice, not one of logic!

Living cells are in a state of dynamic disequilibrium, like a racing cyclist leaning into a curve; if he stops he falls. Until these trillions of molecules designed into billions of structures are convened and assembled, then kick-started into life, they're only a complicated decomposing chemistry set. The blind-chance probability of this event occuring spontaneously is many times smaller than ONE divided by the total number of atoams in the universe! To assert that these intricate, elaborate anda fragile sub-cellular chemicals somehow produced themselves, then assembled in the precise order required for life is simply mysticism.

There is the area of thermodynamic considerations. The SECOND LAW is that all systems tend to the lowest state of information and maximum entropy, all systems go downhill. Fling ten thousand checkers into the air, then examine how they fell. Some will lie neatly, one upon the other. Here and there you may even find a stack of three or four, but it's quite improbable. Now, carefully, start to stack them yourself. Can you stack ten, twenty, three hundred? There comes a point when further accumulation always produces collapse. You cannot stack 300 checkers, nor 300 amino acids, they'll always fall apart. All calculations as to the thermodynamic point of equilibrium of complex biochemicals demonstrate that they would decompose faster than they could assemble, so there was never a warm organic soup. The chemicals required for life would never accumulate in a million infinites - they would merely dissolve.

The creation of life requires that ingredients be formed simultaneously and instantaneously in the same place. The difference of a few moments would find the early arrivals already disintegrated and useless!

Yes, evolution is not only the single greatest false doctrine in our society, but it is also the most idiotic. For life must be kick-started with the breath of life or life cannot exist.

I'll end with part of a poem my husband wrote:

If every house a Maker has,
Does not a tree or blade of grass?
Or butterfly or crimson flower
Disclose a Supernatural Power?
Who paints the sunsets, raises mountains,
Waters earth with living foundations!
Who flings the stars and scents the breeze
With sweet perfume from fruited trees

All shout in praise etheir Maker's Fame
Jehovah, God of Hosts, His Name!
Now do not tear this Name, so Grand
From all the wonders of His Hand
Whose loving gift to you and me
An everlasting estiny!

Or do you choose man's science, proud,
Whose gift to us, the mushroom cloud,
Would take God's Name from rightful place
and steal the future of our race?

Permission to publish
Dr. Betty Martini, D.Hum, Founder
Mission Possible International
9270 River Club Parkway
Duluth, Georgia 30097
770 242-2599

www.mpwhi.com, www.dorway.com, www.wnho.net
Aspartame Toxicity Center, www.holisticmed.com/aspartame
Aspartame Information List, www.mpwhi.com



Krebs Cycle Complexity
by Laurie Easton

[Comment posted 2008-06-09 12:46:58]
I would say that the trycarboxylic acid cycle is a complex system that could in no way arise through chance and could be considered as an irreducibly complex system, such that if any part of it fell out, it would stop working. Suggest you start looking at Intelligent Design for real answers.

BS Biological Science, Honors Biochemistry
1976, UCI






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